Recent advances in Fe-catalyzed C–H aminations using azides as nitrene precursors
Intramolecular aminations of C–H bonds represent an elegant synthetic way to form important N-heterocycles. If suitable nitrene precursors are employed, organometallic complexes are able to catalyze the C–H amination under mild conditions. In the past years, Fe catalysis has emerged as a vigorously developing new (old) discipline. The present review highlights the most important developments in this field through a systematic differentiation between open-shell (radical) and closed-shell (non-radical) mechanisms.
- This article is part of the themed collection: 2019 Catalysis Science & Technology HOT Articles