Issue 17, 2019
From the journal:

Chemical Society Reviews

The growing applications of SuFEx click chemistry†

A. S. Barrow, ORCID logo a   C. J. Smedley, ORCID logo a   Q. Zheng, ORCID logo b   S. Li,c   J. Dongd  and  J. E. Moses*a  

* Corresponding authors

a La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC 3086, Australia
E-mail: j.moses@latrobe.edu.au

b Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA

c School of Chemistry, Sun Yat-Sen University, 135 Xingang Xi Road, Guangzhou 510275, P. R. China

d Key Laboratory of Organofluorine Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Ling-Ling Road, Shanghai 200032, P. R. China

Abstract

SuFEx (Sulfur Fluoride Exchange) is a modular, next generation family of click reactions, geared towards the rapid and reliable assembly of functional molecules. This review discusses the growing number of applications of SuFEx, which can be found in nearly all areas of modern chemistry; from drug discovery to materials science.

Graphical abstract: The growing applications of SuFEx click chemistry

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Article information

DOI
https://doi.org/10.1039/C8CS00960K
Article type
Review Article
Submitted
10 May 2019
First published
31 Jul 2019

Chem. Soc. Rev., 2019,48, 4731-4758

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The growing applications of SuFEx click chemistry

A. S. Barrow, C. J. Smedley, Q. Zheng, S. Li, J. Dong and J. E. Moses, Chem. Soc. Rev., 2019, 48, 4731 DOI: 10.1039/C8CS00960K

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