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Accelerated DNAzyme-based fluorescent nanoprobe for highly sensitive microRNA detection in live cells

Abstract

By assembling DNAzyme on DNA nanowires through DNA hybridization, we have developed a novel accelerated DNAzyme-based fluorescent nanoprobe for fast, sensitive and selective detection of miRNA. Moreover, the strategy was successfully applied for in situ imaging of miRNA-21 in different cell lines.

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Supplementary files

Publication details

The article was received on 04 Nov 2019, accepted on 04 Dec 2019 and first published on 04 Dec 2019


Article type: Communication
DOI: 10.1039/C9CC08598J
Chem. Commun., 2019, Accepted Manuscript

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    Accelerated DNAzyme-based fluorescent nanoprobe for highly sensitive microRNA detection in live cells

    Y. Wu, H. Meng, J. Chen, K. Jiang, R. Yang, Y. Li, K. Zhang, L. Qu, X. Zhang and Z. Li, Chem. Commun., 2019, Accepted Manuscript , DOI: 10.1039/C9CC08598J

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