Jump to main content
Jump to site search


Light-controlled out-of-equilibrium assembly of cyclodextrins in an enzyme-mediated dynamic system

Author affiliations

Abstract

We show that the selective enzymatic synthesis of specific cyclodextrins can be modulated using light. We use enzyme-mediated dynamic combinatorial chemistry to generate a mixture of interconverting linear and cyclic α-1,4-glucans, and employ an azobenzene photoswitch as a template. Using UV or blue light to switch between photostationary states with different azobenzene cis/trans isomeric ratios, we can promote the out-of-equilibrium assembly of either α-cyclodextrin or β-cyclodextrin.

Graphical abstract: Light-controlled out-of-equilibrium assembly of cyclodextrins in an enzyme-mediated dynamic system

Back to tab navigation

Supplementary files

Publication details

The article was received on 30 Oct 2019, accepted on 22 Nov 2019 and first published on 29 Nov 2019


Article type: Communication
DOI: 10.1039/C9CC08452E
Chem. Commun., 2019, Advance Article

  •   Request permissions

    Light-controlled out-of-equilibrium assembly of cyclodextrins in an enzyme-mediated dynamic system

    D. Larsen, P. M. Bjerre and S. R. Beeren, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC08452E

Search articles by author

Spotlight

Advertisements