Convenient Synthesis of Phosphinecarboxamide and Phosphinecarbothioamide by Hydrophosphination of Isocyanate and Isothiocyanate
Reactions of isocyanates with primary and secondary phosphines without solvent at room temperature afforded the corresponding phosphinecarboxamide (RN(H)COPRꞌ2) in excellent yiled. This reaction system is applicable for isothiocyanate. The compounds newly obtained were fully characterized using multielement NMR spectroscopy. In addition, the molecular structure of Cl(CH2)2N(H)COPPh2 was studied by single-crystal X-ray diffraction.