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Issue 100, 2019
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Covalently assembled dopamine nanoparticle as an intrinsic photosensitizer and pH-responsive nanocarrier for potential application in anticancer therapy

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Abstract

We report a novel nanophotosensitizer via one-step covalent assembly of dopamine and genipin. This is the first report unveiling the photodynamic effect of dopamine-based materials. These nanophotosensitizers can also act as pH-responsive drug nanocarriers via a catechol–boronate linkage, thus achieving combined PDT and chemotherapy for highly efficient cancer treatment.

Graphical abstract: Covalently assembled dopamine nanoparticle as an intrinsic photosensitizer and pH-responsive nanocarrier for potential application in anticancer therapy

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Publication details

The article was received on 23 Oct 2019, accepted on 20 Nov 2019 and first published on 21 Nov 2019


Article type: Communication
DOI: 10.1039/C9CC08294H
Chem. Commun., 2019,55, 15057-15060

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    Covalently assembled dopamine nanoparticle as an intrinsic photosensitizer and pH-responsive nanocarrier for potential application in anticancer therapy

    H. Li, Y. Zhao, Y. Jia, C. Qu and J. Li, Chem. Commun., 2019, 55, 15057
    DOI: 10.1039/C9CC08294H

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