Jump to main content
Jump to site search


A hyaluronidase/ATP tandem stimuli-responsive supramolecular assembly

Author affiliations

Abstract

We designed a tandem stimuli-responsive assembly based on a guanidinium-modified calix[5]arene (GC5A-6C) and eosin Y modified hyaluronic acid (EY-HA), which showed hyaluronidase-triggered disassembly and ATP-activated release of EY. Both hyaluronidase and ATP are tumor biomarkers, and therefore, the present system shows potential in precision delivery with respect to tumor phototheranostics.

Graphical abstract: A hyaluronidase/ATP tandem stimuli-responsive supramolecular assembly

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Oct 2019, accepted on 04 Nov 2019 and first published on 05 Nov 2019


Article type: Communication
DOI: 10.1039/C9CC08199B
Chem. Commun., 2019, Advance Article

  •   Request permissions

    A hyaluronidase/ATP tandem stimuli-responsive supramolecular assembly

    J. Gao, H. Yu, F. Chen, X. Hu, Y. Wang and D. Guo, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC08199B

Search articles by author

Spotlight

Advertisements