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Issue 100, 2019
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Aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species

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Abstract

We prepared a nanoprobe through self-assembly of gold nanoclusters (AuNCs) and using FITC-modified hyaluronic acid (HA) for ratiometric sensing of highly reactive oxygen species (hROS). Taking advantage of the aggregation-induced emission (AIE) properties of the self-assembled AuNCs, hROS-responsive cleavage of HA, and the ratiometric signal change of dual-emission, the nanoprobe exhibited excellent performance in imaging hROS in living cells.

Graphical abstract: Aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species

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Publication details

The article was received on 18 Oct 2019, accepted on 22 Nov 2019 and first published on 23 Nov 2019


Article type: Communication
DOI: 10.1039/C9CC08170D
Chem. Commun., 2019,55, 15097-15100

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    Aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species

    X. Ran, Z. Wang, F. Pu, Z. Liu, J. Ren and X. Qu, Chem. Commun., 2019, 55, 15097
    DOI: 10.1039/C9CC08170D

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