Nanomolar detection of adenosine triphosphate (ATP) using a nanostructured fluorescent chemosensing ensemble

Ling-Xi Huang; Qing Guo; Yong Chen; Peter Verwilst; Subin Son; Jia-Bin Wu; Qian-Yong Cao; Jong Seung Kim

doi:10.1039/C9CC08054F

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Nanomolar detection of adenosine triphosphate (ATP) using a nanostructured fluorescent chemosensing ensemble†

Ling-Xi Huang,‡^a Qing Guo,‡^a Yong Chen,

^b Peter Verwilst,

^c Subin Son,

^c Jia-Bin Wu,^a Qian-Yong Cao

*^a and Jong Seung Kim

*^c

Author affiliations

* Corresponding authors

^a Department of Chemistry, Nanchang University, Nanchang 330031, P. R. China
E-mail: cqyong@ncu.edu.cn
Fax: +86 791-83969386

^b Institute for Advanced Study, Nanchang University, Nanchang 330031, China

^c Department of Chemistry, Korea University, Seoul 02841, Korea
E-mail: jongskim@korea.ac.kr

Abstract

We report a novel nanostructured chemosensing ensemble PyNp-C13/UD, obtained by self-assembling uranine dye (UD) and an amphiphilic pyridinium salt PyNp-C13. The ensemble was developed for the fluorescence turn-on sensing of ATP in aqueous solutions and inside living cells. The assembly operates via an indicator displacement assay (IDA) method with an ultra-low detection limit of 6.8 nM.

This article is part of the themed collection: The Mechanics of Supramolecular Chemistry

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Article information

DOI: https://doi.org/10.1039/C9CC08054F
Article type: Communication
Submitted: 14 Oct 2019
Accepted: 29 Oct 2019
First published: 01 Nov 2019

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Chem. Commun., 2019,55, 14135-14138

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Nanomolar detection of adenosine triphosphate (ATP) using a nanostructured fluorescent chemosensing ensemble

L. Huang, Q. Guo, Y. Chen, P. Verwilst, S. Son, J. Wu, Q. Cao and J. S. Kim, Chem. Commun., 2019, 55, 14135 DOI: 10.1039/C9CC08054F

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Chemical Communications

Nanomolar detection of adenosine triphosphate (ATP) using a nanostructured fluorescent chemosensing ensemble†

Abstract

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Nanomolar detection of adenosine triphosphate (ATP) using a nanostructured fluorescent chemosensing ensemble

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