Issue 96, 2019
From the journal:

Chemical Communications

Optically-controlled supramolecular self-assembly of an antibiotic for antibacterial regulation†

Xuancheng Fu,ab   Haotian Bai,a   Ruilian Qi,a   Hao Zhao,ab   Ke Peng,ab   Fengting Lv, ORCID logo a   Libing Liu ORCID logo *ab  and  Shu Wang*ab  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China
E-mail: wangshu@iccas.ac.cn, liulibing@iccas.ac.cn

b College of Chemistry, University of Chinese Academy of Sciences, Beijing 100049, P. R. China

Abstract

We report a supramolecular photo-responsive antibiotic (azobenzene-norfloxacin/αCD). This supramolecule exhibited a higher “on–off” ratio of antibacterial ability than azobenzene-norfloxacin alone under UV irradiation. It offers an approach to efficiently regulate the activity of antibiotics by combining the supramolecular and light-regulating strategies together.

Graphical abstract: Optically-controlled supramolecular self-assembly of an antibiotic for antibacterial regulation

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Article information

DOI
https://doi.org/10.1039/C9CC07999H
Article type
Communication
Submitted
12 Oct 2019
Accepted
07 Nov 2019
First published
08 Nov 2019

Chem. Commun., 2019,55, 14466-14469

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Optically-controlled supramolecular self-assembly of an antibiotic for antibacterial regulation

X. Fu, H. Bai, R. Qi, H. Zhao, K. Peng, F. Lv, L. Liu and S. Wang, Chem. Commun., 2019, 55, 14466 DOI: 10.1039/C9CC07999H

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