Jump to main content
Jump to site search


Metal-free α-arylation of α-fluoro-α-nitroacetamides employing diaryliodonium salts

Author affiliations

Abstract

Herein, we present a mild and efficient metal-free arylation of α-fluoro-α-nitroacetamides employing diaryliodonium salts. A broad range of diaryliodonium salts and α-fluoro-α-nitroacetamides containing sensitive functional groups was successfully employed in this protocol to yield the arylated products in good yields. The synthetic value of this novel protocol was further highlighted by extending the α-arylation to α-cyano-α-fluoroacetamides.

Graphical abstract: Metal-free α-arylation of α-fluoro-α-nitroacetamides employing diaryliodonium salts

Back to tab navigation

Supplementary files

Publication details

The article was received on 07 Oct 2019, accepted on 27 Nov 2019 and first published on 27 Nov 2019


Article type: Communication
DOI: 10.1039/C9CC07859B
Chem. Commun., 2020, Advance Article

  •   Request permissions

    Metal-free α-arylation of α-fluoro-α-nitroacetamides employing diaryliodonium salts

    M. K. Zaheer, E. Gupta, R. Kant and K. Mohanan, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC07859B

Search articles by author

Spotlight

Advertisements