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Issue 92, 2019
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Visible-light-induced intramolecular sp3 C–H oxidation of 2-alkyl-substituted benzamides for the synthesis of functionalized iminoisobenzofurans

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Abstract

We have developed a protocol for the synthesis of functionalized iminoisobenzofurans by means of visible-light-induced intramolecular cyclization reactions of 2-alkyl-substituted benzamides. This one step-economical protocol, which involves intramolecular sp3 C–O bond formation, features mild reaction conditions, exclusive chemoselectivity, and high yields.

Graphical abstract: Visible-light-induced intramolecular sp3 C–H oxidation of 2-alkyl-substituted benzamides for the synthesis of functionalized iminoisobenzofurans

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Publication details

The article was received on 04 Oct 2019, accepted on 25 Oct 2019 and first published on 25 Oct 2019


Article type: Communication
DOI: 10.1039/C9CC07791J
Chem. Commun., 2019,55, 13908-13911

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    Visible-light-induced intramolecular sp3 C–H oxidation of 2-alkyl-substituted benzamides for the synthesis of functionalized iminoisobenzofurans

    L. Wu, Y. Hao, Y. Liu and Q. Wang, Chem. Commun., 2019, 55, 13908
    DOI: 10.1039/C9CC07791J

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