Jump to main content
Jump to site search


NIRF turn-on nanoparticles based on the tumor microenvironment for monitoring intracellular protein delivery

Author affiliations

Abstract

A dual responsive NIRF turn-on protein delivery system incorporating an NIRF turn-on probe and protein into one single nanoparticle has been constructed. It can be taken up efficiently by A549 cells, where protein release and NIRF recovery happen simultaneously in response to low pH and excessive H2O2. This work provides a novel system for monitoring intracellular protein delivery.

Graphical abstract: NIRF turn-on nanoparticles based on the tumor microenvironment for monitoring intracellular protein delivery

Back to tab navigation

Supplementary files

Publication details

The article was received on 03 Oct 2019, accepted on 18 Nov 2019 and first published on 18 Nov 2019


Article type: Communication
DOI: 10.1039/C9CC07768E
Chem. Commun., 2019, Advance Article

  •   Request permissions

    NIRF turn-on nanoparticles based on the tumor microenvironment for monitoring intracellular protein delivery

    H. Xu, Y. Wang, Z. Pei, W. Ji and Y. Pei, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC07768E

Search articles by author

Spotlight

Advertisements