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A bright NIR-II fluorescent probe for breast carcinoma imaging and image-guided surgery

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Abstract

A novel bright near-infrared II (NIR-II, 1000–1700 nm) fluorescent probe with excellent water-solubility, superior photostability, and excellent in vitro and in vivo biocompatibility was facilely synthesized for in vivo biomedical imaging of xenograft breast tumor and chemically induced spontaneous breast carcinoma. To the best of our knowledge, it is the first time that the superior practical applications of this NIR-II probe in dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma imaging and image-guided rat carcinoma surgery were demonstrated.

Graphical abstract: A bright NIR-II fluorescent probe for breast carcinoma imaging and image-guided surgery

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Publication details

The article was received on 01 Oct 2019, accepted on 04 Nov 2019 and first published on 05 Nov 2019


Article type: Communication
DOI: 10.1039/C9CC07694H
Chem. Commun., 2019, Advance Article

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    A bright NIR-II fluorescent probe for breast carcinoma imaging and image-guided surgery

    X. Zeng, L. Xie, D. Chen, S. Li, J. Nong, B. Wang, L. Tang, Q. Li, Y. Li, Z. Deng, X. Hong, M. Wu and Y. Xiao, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC07694H

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