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Cell-penetrating peptide-modified quantum dots as a ratiometric nanobiosensor for the simultaneous sensing and imaging of lysosomes and extracellular pH

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Abstract

The selective measurement of cellular pH at specific regions is significant for the in-depth study of cell functions and pathological processes. Herein, we combined our previously developed rhodamine B-labeled cell-penetrating peptide spirolactam derivative with quantum dots to create a ratiometric nanobiosensor for the simultaneous sensing and imaging of lysosomes and extracellular pH.

Graphical abstract: Cell-penetrating peptide-modified quantum dots as a ratiometric nanobiosensor for the simultaneous sensing and imaging of lysosomes and extracellular pH

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Publication details

The article was received on 27 Sep 2019, accepted on 16 Nov 2019 and first published on 18 Nov 2019


Article type: Communication
DOI: 10.1039/C9CC07596H
Chem. Commun., 2020, Advance Article

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    Cell-penetrating peptide-modified quantum dots as a ratiometric nanobiosensor for the simultaneous sensing and imaging of lysosomes and extracellular pH

    Y. Yang, M. Xia, S. Zhang and X. Zhang, Chem. Commun., 2020, Advance Article , DOI: 10.1039/C9CC07596H

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