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Sensitive discrimination of glycoproteins and cell differentiation with an array sensing platform exploiting pyrene-derived amphiphile/surfactant assemblies

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Abstract

An array sensing platform exploiting phenyl boronic acid-functionalized pyrene amphiphile/surfactant assemblies is constructed for glycoprotein discrimination, achieving a discrimination sensitivity of 50 nM. Gastric cancer cell lines of various differentiation grades are successfully discriminated, demonstrating its great potential in sensitive differentiation of glycoprotein-related samples in biomedical diagnosis.

Graphical abstract: Sensitive discrimination of glycoproteins and cell differentiation with an array sensing platform exploiting pyrene-derived amphiphile/surfactant assemblies

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Publication details

The article was received on 25 Sep 2019, accepted on 17 Oct 2019 and first published on 17 Oct 2019


Article type: Communication
DOI: 10.1039/C9CC07515A
Chem. Commun., 2019, Advance Article

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    Sensitive discrimination of glycoproteins and cell differentiation with an array sensing platform exploiting pyrene-derived amphiphile/surfactant assemblies

    X. Lin, L. Gao, J. Wang and X. Chen, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC07515A

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