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Issue 98, 2019
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Polymerization-driven successive collapse of DNA dominoes enabling highly sensitive cancer gene diagnosis

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Abstract

We propose a novel fluorescence assay method by designing a polymerization-driven DNA dominoes collapse (PDDC) strategy, enabling highly sensitive detection of p53 gene (as a model analyte) and single nucleotide polymorphism analysis.

Graphical abstract: Polymerization-driven successive collapse of DNA dominoes enabling highly sensitive cancer gene diagnosis

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Publication details

The article was received on 24 Sep 2019, accepted on 17 Nov 2019 and first published on 18 Nov 2019


Article type: Communication
DOI: 10.1039/C9CC07508A
Chem. Commun., 2019,55, 14797-14800

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    Polymerization-driven successive collapse of DNA dominoes enabling highly sensitive cancer gene diagnosis

    H. Dong, B. Lu, J. Wang, J. Xie, K. Liu, L. Jia and J. Zhuang, Chem. Commun., 2019, 55, 14797
    DOI: 10.1039/C9CC07508A

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