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A lysosome-specific near-infrared fluorescent probe for in vitro cancer cell detection and non-invasive in vivo imaging

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Abstract

Near-infrared (NIR) fluorescent probes have been developed as potential bio-materials having profound applications in diagnosis and clinical practice. Herein, we wish to disclose a highly photostable ultra-bright NIR probe for the specific detection of lysosomes in numerous cell lines. Furthermore, the applicability of the developed NIR probe was evaluated for in vivo imaging.

Graphical abstract: A lysosome-specific near-infrared fluorescent probe for in vitro cancer cell detection and non-invasive in vivo imaging

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Publication details

The article was received on 18 Sep 2019, accepted on 27 Oct 2019 and first published on 28 Oct 2019


Article type: Communication
DOI: 10.1039/C9CC07322A
Chem. Commun., 2019, Advance Article

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    A lysosome-specific near-infrared fluorescent probe for in vitro cancer cell detection and non-invasive in vivo imaging

    R. Mengji, C. Acharya, V. Vangala and A. Jana, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC07322A

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