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A NIR-emitting cyanine with large Stokes shifts for live cell imaging: large impact of the phenol group on emission

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Abstract

There are a limited number of near-infrared (NIR) emitting (λem = 700–900 nm) molecular probes for imaging applications. A NIR-emitting probe that exhibits emission at ∼800 nm with a large Stokes shift was synthesized and found to exhibit excellent selectivity towards mitochondria for live-cell imaging. The photophysical properties were attributed to an excited “cyanine structure” via intramolecular charge transfer (ICT) involving a phenol group.

Graphical abstract: A NIR-emitting cyanine with large Stokes shifts for live cell imaging: large impact of the phenol group on emission

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Publication details

The article was received on 02 Sep 2019, accepted on 26 Sep 2019 and first published on 26 Sep 2019


Article type: Communication
DOI: 10.1039/C9CC06831G
Chem. Commun., 2019, Advance Article

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    A NIR-emitting cyanine with large Stokes shifts for live cell imaging: large impact of the phenol group on emission

    D. Dahal, L. McDonald, S. Pokhrel, S. Paruchuri, M. Konopka and Y. Pang, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC06831G

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