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Corroles and corrole/transferrin nanoconjugates as candidates for sonodynamic therapy

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Abstract

We report the utility of water-soluble corroles and also protein-coated nanoparticles (NPs) of lipophilic corroles as potent candidates for sonodynamic therapy (SDT), through the detection and quantification of the singlet oxygen that is produced by the ultrasonic irradiation of their aqueous solutions. Preliminary results on a cancer cell line provide evidence for the true utility of the NPs for SDT.

Graphical abstract: Corroles and corrole/transferrin nanoconjugates as candidates for sonodynamic therapy

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Publication details

The article was received on 22 Aug 2019, accepted on 13 Sep 2019 and first published on 27 Sep 2019


Article type: Communication
DOI: 10.1039/C9CC06494J
Chem. Commun., 2019, Advance Article

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    Corroles and corrole/transferrin nanoconjugates as candidates for sonodynamic therapy

    V. K. Sharma, A. Mahammed, M. Soll, B. Tumanskii and Z. Gross, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC06494J

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