Jump to main content
Jump to site search


A Newly Designed Heterodiene and Its Application to Construct Six-Membered Heterocycles Containing an N-O Bond

Abstract

A new type of zwitterionic nitrosoalkenes generated in situ from dehydrohalogenation of α-halo-N-alkylhydroxamic acids was designed. [4+2] cycloadditions of  this heterodiene to olefines provide a facile route to construct six-membered heterocycles containing an N-O bond and a new protocol to 1,2-syn carbohydroxylate alkenes with a hydroxyl and acetamide group. DFT Calculations support a concerted cycloaddition pathway and the solvent HFIP can stabilize the transition state through H-bonding interaction.

Back to tab navigation

Supplementary files

Publication details

The article was accepted on 12 Aug 2019 and first published on 12 Aug 2019


Article type: Communication
DOI: 10.1039/C9CC05694G
Chem. Commun., 2019, Accepted Manuscript

  •   Request permissions

    A Newly Designed Heterodiene and Its Application to Construct Six-Membered Heterocycles Containing an N-O Bond

    W. Ji, C. Li, H. Chen, Z. Yu and X. Liao, Chem. Commun., 2019, Accepted Manuscript , DOI: 10.1039/C9CC05694G

Search articles by author

Spotlight

Advertisements