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Mitochondria-targeted Ir@AuNRs as bifunctional therapeutic agents for hypoxia imaging and photothermal therapy

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Abstract

Ir(III) complex modified gold nanorods, Ir@AuNRs, were developed as mitochondria-targeted theranostic nanoagents. Their hypoxia imaging and photothermal therapeutic properties were demonstrated in vitro and in vivo.

Graphical abstract: Mitochondria-targeted Ir@AuNRs as bifunctional therapeutic agents for hypoxia imaging and photothermal therapy

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Publication details

The article was received on 19 Jul 2019, accepted on 05 Aug 2019 and first published on 05 Aug 2019


Article type: Communication
DOI: 10.1039/C9CC05610F
Chem. Commun., 2019, Advance Article

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    Mitochondria-targeted Ir@AuNRs as bifunctional therapeutic agents for hypoxia imaging and photothermal therapy

    L. Ke, C. Zhang, X. Liao, K. Qiu, T. W. Rees, Y. Chen, Z. Zhao, L. Ji and H. Chao, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC05610F

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