Jump to main content
Jump to site search


Enzymatic kinetic resolution of chiral sulfoxides – an enantiocomplementary approach

Author affiliations

Abstract

A new enzymatic assay for the preparation of chiral sulfoxides that is enantiocomplementary to the known (S)-enantiomer-reducing activity of methionine sulfoxide reductase A (MsrA) is described. To this end, we have utilized the enzyme DMSO reductase (DmsABC), recently discovered by us being highly upregulated in stationary phase E. coli bacteria.

Graphical abstract: Enzymatic kinetic resolution of chiral sulfoxides – an enantiocomplementary approach

Back to tab navigation

Supplementary files

Publication details

The article was received on 16 Jul 2019, accepted on 08 Aug 2019 and first published on 08 Aug 2019


Article type: Communication
DOI: 10.1039/C9CC05470G
Chem. Commun., 2019, Advance Article

  •   Request permissions

    Enzymatic kinetic resolution of chiral sulfoxides – an enantiocomplementary approach

    V. Nosek and J. Míšek, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC05470G

Search articles by author

Spotlight

Advertisements