Yannan Zhu, Hongxing Jin and You Huang
Chem. Commun., 2019,55, 10135-10137
DOI:
10.1039/C9CC05276C,
Communication
An unprecedented [3+3]-annulation of p-quinamines and nitrile imines was developed, affording a series of 1,2,4-triazinone derivatives in moderate to excellent yields with excellent diastereoselectivity. This cycloaddition expands the scope of p-quinamines to the construction of six-membered nitrogen-containing heterocyclic compounds.
![Graphical abstract: DABCO-mediated [3+3] annulation of para-quinamines: access to functionalized 1,2,4-triazinone derivatives](/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=C9CC05276C "Graphical abstract")
