Jump to main content
Jump to site search

Issue 69, 2019
Previous Article Next Article

Integrated magneto-fluorescence nanobeads for ultrasensitive glycoprotein detection using antibody coupled boronate-affinity recognition

Author affiliations

Abstract

Herein, we report a novel magnet-mediated antibody-boronate sandwich-typed assay (ABSTA) strategy for the ultrasensitive, specific, rapid, and enzyme-free detection of glycoproteins in complex samples. The proposed ABSTA method exhibited ultrahigh sensitivity for HCG with a detection limit of 0.19 mIU mL−1, which is approximately 40-fold lower than that of conventional sandwich enzyme immunoassay.

Graphical abstract: Integrated magneto-fluorescence nanobeads for ultrasensitive glycoprotein detection using antibody coupled boronate-affinity recognition

Back to tab navigation

Supplementary files

Publication details

The article was received on 26 Jun 2019, accepted on 05 Aug 2019 and first published on 06 Aug 2019


Article type: Communication
DOI: 10.1039/C9CC04902A
Chem. Commun., 2019,55, 10312-10315

  •   Request permissions

    Integrated magneto-fluorescence nanobeads for ultrasensitive glycoprotein detection using antibody coupled boronate-affinity recognition

    J. Chen, L. Hao, Y. Wu, T. Lin, X. Li, Y. Leng, X. Huang and Y. Xiong, Chem. Commun., 2019, 55, 10312
    DOI: 10.1039/C9CC04902A

Search articles by author

Spotlight

Advertisements