Jump to main content
Jump to site search

Issue 72, 2019
Previous Article Next Article

Dual function of carbon tetrachloride: synthesis of chlorinated heterocycles

Author affiliations

Abstract

An efficient tandem approach to invent highly chlorinated and structurally diversified dihydropyridine fused heterocycles from easily accessible ortho-alkynylaldehydes and primary amines under metal-free conditions via four sequential bond formations is described. The proposed tandem route proceeds via a carbon tetrachloride-mediated 6-endo-dig ring closure followed by nucleophilic attack of the trichloromethyl anion.

Graphical abstract: Dual function of carbon tetrachloride: synthesis of chlorinated heterocycles

Back to tab navigation

Supplementary files

Article information


Submitted
20 Jun 2019
Accepted
09 Aug 2019
First published
12 Aug 2019

Chem. Commun., 2019,55, 10721-10724
Article type
Communication

Dual function of carbon tetrachloride: synthesis of chlorinated heterocycles

S. Kumar, R. K. Saunthwal, K. M. Saini and A. K. Verma, Chem. Commun., 2019, 55, 10721
DOI: 10.1039/C9CC04746H

Social activity

Search articles by author

Spotlight

Advertisements