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Tracking lysosomal polarity variation in inflamed, obese, and cancer mice guided by a fluorescence sensing strategy

Abstract

In this work, a robust probe MND-Lys was proposed for monitoring lysosomal polarity. The probe firstly achieved monitoring the intrinsic polarity variance in embryos and adult zebrafish. Besides obviously discriminating tumors from normal ones, the probe also enabled tracing polarity changes in inflammatory and obese mice for the first time.

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Publication details

The article was received on 20 Jun 2019, accepted on 24 Jul 2019 and first published on 25 Jul 2019


Article type: Communication
DOI: 10.1039/C9CC04739E
Chem. Commun., 2019, Accepted Manuscript

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    Tracking lysosomal polarity variation in inflamed, obese, and cancer mice guided by a fluorescence sensing strategy

    J. Yin, M. Peng and W. Lin, Chem. Commun., 2019, Accepted Manuscript , DOI: 10.1039/C9CC04739E

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