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Issue 83, 2019
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The remarkable UV light invulnerability of thymine GNA dinucleotides

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Abstract

We herein demonstrate the UV resistance of glycol nucleic acid (GNA) dinucleotides. This resistance sustains the hypothesis of GNA as a nucleic acid prebiotic ancestor on early Earth, a time of intense solar UV light. Such photorobustness, due to the absence of intrastrand base stacking, could offer an opportunity for nanodevice development requiring challenging UV conditions.

Graphical abstract: The remarkable UV light invulnerability of thymine GNA dinucleotides

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Publication details

The article was received on 06 Jun 2019, accepted on 25 Sep 2019 and first published on 25 Sep 2019


Article type: Communication
DOI: 10.1039/C9CC04355A
Chem. Commun., 2019,55, 12571-12574

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    The remarkable UV light invulnerability of thymine GNA dinucleotides

    S. Coantic-Castex, A. Martinez, D. Harakat, D. Guillaume and P. Clivio, Chem. Commun., 2019, 55, 12571
    DOI: 10.1039/C9CC04355A

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