Accurate detection of intracellular microRNAs using functional Mo2C quantum dots nanoprobe

Wenhao Dai; Huiting Lu; Fan Yang; Haifeng Dong; Xueji Zhang

doi:10.1039/C9CC04261J

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Accurate detection of intracellular microRNAs using functional Mo₂C quantum dots nanoprobe†

Wenhao Dai,^a Huiting Lu,

^b Fan Yang,^a Haifeng Dong

*^a and Xueji Zhang

*^ac

Author affiliations

* Corresponding authors

^a Research Center for Bioengineering and Sensing Technology, School of Chemistry and Bioengineering, University of Science & Technology Beijing, Beijing 100083, P. R. China
E-mail: hfdong@ustb.edu.cn, zhangxueji@ustb.edu.cn

^b School of Chemistry & Biological Engineering University of Science & Technology Beijing, Beijing 100083, P. R. China

^c School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, Guangdong 518060, P. R. China

Abstract

A programmable molecular beacon (MB) with a good discrimination capability for mature and precursor microRNAs was loaded onto the surface of Mo₂C quantum dots (QDs) for accurate detection of intracellular mature microRNAs.

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Article information

DOI: https://doi.org/10.1039/C9CC04261J
Article type: Communication
Submitted: 03 Jun 2019
Accepted: 09 Aug 2019
First published: 10 Aug 2019

Download Citation

Chem. Commun., 2019,55, 10615-10618

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Accurate detection of intracellular microRNAs using functional Mo₂C quantum dots nanoprobe

W. Dai, H. Lu, F. Yang, H. Dong and X. Zhang, Chem. Commun., 2019, 55, 10615 DOI: 10.1039/C9CC04261J

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Chemical Communications