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Issue 64, 2019
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Overcoming inaccessibility of fluorinated imines – synthesis of functionalized amines from readily available fluoroacetamides

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Abstract

Although imines are convenient substrates for the synthesis of functionalized amines, they may be hard to obtain, as in the case of fluorinated imines. To aid in overcoming this issue, we propose a protocol of corresponding amine synthesis from simple fluoroacetic acid-derived amides using Schwartz's reagent.

Graphical abstract: Overcoming inaccessibility of fluorinated imines – synthesis of functionalized amines from readily available fluoroacetamides

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Article information


Submitted
28 May 2019
Accepted
05 Jul 2019
First published
05 Jul 2019

Chem. Commun., 2019,55, 9436-9439
Article type
Communication

Overcoming inaccessibility of fluorinated imines – synthesis of functionalized amines from readily available fluoroacetamides

P. J. Czerwiński and B. Furman, Chem. Commun., 2019, 55, 9436
DOI: 10.1039/C9CC04111G

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