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Issue 51, 2019
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A simple mix-and-read bacteria detection system based on a DNAzyme and a molecular beacon

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Abstract

Here, we describe a simple mix-and-read method for the detection of specific bacterial strains that uses a DNAzyme and a molecular beacon to generate a signal. We have greatly improved upon the previously described DNAzyme-based bacteria detection method by eliminating a tedious preparation step while maintaining detection sensitivity.

Graphical abstract: A simple mix-and-read bacteria detection system based on a DNAzyme and a molecular beacon

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Article information


Submitted
15 May 2019
Accepted
24 May 2019
First published
24 May 2019

Chem. Commun., 2019,55, 7358-7361
Article type
Communication
Author version available

A simple mix-and-read bacteria detection system based on a DNAzyme and a molecular beacon

T. Cao, Y. Wang, L. Zhao, Y. Wang, Y. Tao, J. A. Heyman, D. A. Weitz, Y. Zhou and X. Zhang, Chem. Commun., 2019, 55, 7358
DOI: 10.1039/C9CC03746B

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