Issue 59, 2019

Water gated contrast switching with polymer–silica hybrid nanoparticles

Abstract

Bioresponsive contrast agents can provide smart signaling in MRI. In wrapping pore functionalised Gd-DOTA mesoporous silica nanoparticles with pH-responsive poly(acrylic acid), exchange between pore and bulk water can be reversibly switched by local pH. The generated high contrast then exhibits a large amplitude switch in a manner relevant to environmentally responsive imaging.

Graphical abstract: Water gated contrast switching with polymer–silica hybrid nanoparticles

Supplementary files

Article information

Article type
Communication
Submitted
29 Apr 2019
Accepted
02 Jul 2019
First published
02 Jul 2019

Chem. Commun., 2019,55, 8540-8543

Water gated contrast switching with polymer–silica hybrid nanoparticles

J. Pellico, C. M. Ellis, J. Miller and J. J. Davis, Chem. Commun., 2019, 55, 8540 DOI: 10.1039/C9CC03312B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements