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A Fluorogenic BODIPY Molecular Rotor as Apoptosis Marker

Abstract

Based on BODIPY molecular rotor and zinc-dipicolylamine receptor, we designed a fluorogenic probe for detection of apoptosis. Being poorly emissive in solution and with healthy cells, it selectively binds phosphatidylserine of early apoptotic cells and internalizes into late apoptoric cells, lighting up its green fluorescence.

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Publication details

The article was received on 26 Apr 2019, accepted on 15 May 2019 and first published on 15 May 2019


Article type: Communication
DOI: 10.1039/C9CC03242H
Chem. Commun., 2019, Accepted Manuscript

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    A Fluorogenic BODIPY Molecular Rotor as Apoptosis Marker

    P. Ashokkumar, A. H. Ashoka, M. Collot, A. Das and A. S. Klymchenko, Chem. Commun., 2019, Accepted Manuscript , DOI: 10.1039/C9CC03242H

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