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An ultrasensitive ratiometric fluorescent probe based on ICT-PET-FRET mechanism for the quantitative measurement of pH values in endoplasmic reticulum (ER)

Abstract

Herein, we present a dual-site ratiometric fluorescent probe based on ICT-PET-FRET mechanism for the detection of pH in ER. The probe showed highly sensitive response to pH in the range 5.0-7.2, and could be applied for the quantitative measurement of the pH values in ER during ER stress and dexamethanose-induced stimulation.

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Supplementary files

Publication details

The article was received on 22 Apr 2019, accepted on 13 Aug 2019 and first published on 15 Aug 2019


Article type: Communication
DOI: 10.1039/C9CC03114F
Chem. Commun., 2019, Accepted Manuscript

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    An ultrasensitive ratiometric fluorescent probe based on ICT-PET-FRET mechanism for the quantitative measurement of pH values in endoplasmic reticulum (ER)

    B. Dong, W. Song, Y. Lu, X. Kong, A. H. Mehmood and W. Lin, Chem. Commun., 2019, Accepted Manuscript , DOI: 10.1039/C9CC03114F

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