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Crackled Nanocapsules: “Imperfect” Structure for Enzyme Immobilization


Herein, the first example of crackled organosilica nanocapsules (CONs) is reported to directly immobilize enzymes without any further chemical modification. Enzymes are adsorbed on both the exterior and interior surface of CONs, integrating the merits of adsorption and encapsulation. When served for Candida rugosa lipase (CRL) immobilization, CONs displayed higher enzyme loading, lower enzyme leaching, and elevated enzyme activity, compared to conventional non-crackled nanocapsules/particles.

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Publication details

The article was received on 11 Apr 2019, accepted on 17 May 2019 and first published on 17 May 2019

Article type: Communication
DOI: 10.1039/C9CC02797A
Chem. Commun., 2019, Accepted Manuscript

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    Crackled Nanocapsules: “Imperfect” Structure for Enzyme Immobilization

    Q. Huo, J. Zhao, W. Li, D. Yang, S. Zhang, J. Shi and Z. Jiang, Chem. Commun., 2019, Accepted Manuscript , DOI: 10.1039/C9CC02797A

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