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Triangeliphthalides A–D: bioactive phthalide trimers with new skeletons from Angelica sinensis and their production mechanism

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Abstract

Triangeliphthalides A–D (1–4), four novel phthalide trimers with two new linkage styles, were isolated from Angelica sinensis, together with two related phthalide dimers (5–6). Their structures including absolute configurations were determined. The production mechanism of phthalide polymers was proposed, and their bioactivities were also evaluated.

Graphical abstract: Triangeliphthalides A–D: bioactive phthalide trimers with new skeletons from Angelica sinensis and their production mechanism

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Publication details

The article was received on 08 Apr 2019, accepted on 30 Apr 2019 and first published on 02 May 2019


Article type: Communication
DOI: 10.1039/C9CC02681A
Chem. Commun., 2019, Advance Article

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    Triangeliphthalides A–D: bioactive phthalide trimers with new skeletons from Angelica sinensis and their production mechanism

    J. Zou, G. Chen, H. Zhao, X. Wang, Z. Zhang, Y. Qu, R. He, K. So, X. Yao and H. Gao, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC02681A

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