Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 22nd May 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.



Chiroptical sensing of unprotected amino acids, hydroxy acids, amino alcohols, amines and carboxylic acids with metal salts

Author affiliations

Abstract

Optical chirality sensing of unprotected amino acids, hydroxy acids, amino alcohols, amines and carboxylic acids based on a practical mix-and-measure protocol with readily available copper, iron, palladium, manganese, cerium or rhodium salts is demonstrated. The generation of strong cotton effects allows quantitative ee analysis of small sample amounts with high speed. In contrast to previously reported assays the use of chromophoric reporter ligands and the control of metal coordination kinetics and redox chemistry are not necessary which greatly simplifies the sensing procedure with the benefit of reduced waste production and cost.

Graphical abstract: Chiroptical sensing of unprotected amino acids, hydroxy acids, amino alcohols, amines and carboxylic acids with metal salts

Back to tab navigation

Supplementary files

Publication details

The article was received on 01 Apr 2019, accepted on 08 May 2019 and first published on 08 May 2019


Article type: Communication
DOI: 10.1039/C9CC02525A
Chem. Commun., 2019, Advance Article

  •   Request permissions

    Chiroptical sensing of unprotected amino acids, hydroxy acids, amino alcohols, amines and carboxylic acids with metal salts

    C. C. Lynch, Z. A. De los Santos and C. Wolf, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC02525A

Search articles by author

Spotlight

Advertisements