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Issue 38, 2019
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Anti-inflammatory marine cyclic peptide stylissatin A and its derivatives inhibit differentiation of murine preadipocytes

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Abstract

Stylissatin A, an anti-inflammatory cyclic heptapeptide, and its derivatives potently inhibited the differentiation of preadipocytes and reduced triglyceride accumulation in mature adipocytes, with little cytotoxicity. Our studies might contribute to the development of leads for new anti-inflammatory and anti-obesity agents.

Graphical abstract: Anti-inflammatory marine cyclic peptide stylissatin A and its derivatives inhibit differentiation of murine preadipocytes

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Article information


Submitted
01 Apr 2019
Accepted
10 Apr 2019
First published
11 Apr 2019

Chem. Commun., 2019,55, 5471-5474
Article type
Communication
Author version available

Anti-inflammatory marine cyclic peptide stylissatin A and its derivatives inhibit differentiation of murine preadipocytes

M. Zhang, T. Sunaba, Y. Sun, K. Sasaki, H. Isoda, H. Kigoshi and M. Kita, Chem. Commun., 2019, 55, 5471
DOI: 10.1039/C9CC02517K

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