Yuhong Lin, Lili Jiang, Yuqing Huang, Yuling Yang, Yu He, Chunhua Lu and Huanghao Yang
Chem. Commun., 2019,55, 5387-5390
DOI:
10.1039/C9CC02365H,
Communication
DNA-triggered reversible isolation and recovery of circulating tumor cells (CTCs) is presented based on a multivalent dual-specific aptamer-tethered rolling circle amplification (MA-RCA) network. The multivalent binding sites endow the MA-RCA network with a strong binding ability towards CTCs, and the repeated cell capture/release processes are also actualized in a noninvasive manner.
