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A DNA encoding loop program: the snowball effect enhanced microRNA visualization in living cells

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Abstract

Here we report a convenient, universal “DNA encoding loop program (DELP)” strategy that significantly enhanced the sensitivity of subcellular imaging of microRNA. The assay relies on the dynamic, ultrafast clustering of multiple plasmonic gold nanoparticles actuated by a DNA-programmed recycling process.

Graphical abstract: A DNA encoding loop program: the snowball effect enhanced microRNA visualization in living cells

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Publication details

The article was received on 19 Mar 2019, accepted on 25 Apr 2019 and first published on 25 Apr 2019


Article type: Communication
DOI: 10.1039/C9CC02169H
Chem. Commun., 2019, Advance Article

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    A DNA encoding loop program: the snowball effect enhanced microRNA visualization in living cells

    J. Lv, Z. Zhou and R. Qian, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC02169H

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