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Phenyleneethynylene trimer-based rigid-flexible [2+2] macrocycles for nucleic acid labelling in live cells

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Abstract

Fluorescent macromolecules were developed for intracellular labeling in live cells. Coupling rigid rod phenyleneethynylene trimers with flexible amphiphilic diamines via the imine-bond formation chemistry yielded rigid–flexible [2+2] macromolecules showing nucleic acid selectivity and nontoxicity in live cells.

Graphical abstract: Phenyleneethynylene trimer-based rigid-flexible [2+2] macrocycles for nucleic acid labelling in live cells

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Publication details

The article was received on 18 Mar 2019, accepted on 25 Apr 2019 and first published on 25 Apr 2019


Article type: Communication
DOI: 10.1039/C9CC02162K
Chem. Commun., 2019, Advance Article

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    Phenyleneethynylene trimer-based rigid-flexible [2+2] macrocycles for nucleic acid labelling in live cells

    J. H. Moon, P. Manandhar, H. Torabi, M. R. Rohman, L. Mathivathanan, K. H. Lee and S. Irle, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC02162K

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