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Issue 42, 2019
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Multifunctional isoquinoline-oxazoline ligands of chemical and biological importance

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Abstract

Multifunctional isoquinoline-oxazolines (MIQOXs) were conceived and synthesized from commercially available chiral amino acids. The multifunctional role of MIQOXs was demonstrated by Pd-catalyzed highly enantioselective addition of arylboronic acids to nitrostyrenes, and by the discovery of novel antifungal candidates.

Graphical abstract: Multifunctional isoquinoline-oxazoline ligands of chemical and biological importance

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Publication details

The article was received on 05 Mar 2019, accepted on 25 Apr 2019 and first published on 25 Apr 2019


Article type: Communication
DOI: 10.1039/C9CC01790A
Chem. Commun., 2019,55, 5902-5905

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    Multifunctional isoquinoline-oxazoline ligands of chemical and biological importance

    W. Li, G. Wang, J. Lai and S. Li, Chem. Commun., 2019, 55, 5902
    DOI: 10.1039/C9CC01790A

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