A fluorescent probe decorated with an alkynyl ester unit (e.g. propiolate) displayed a selective turn-on type fluorescent response towards cysteine. Following a sequential addition–cyclisation pathway mediated by the addition of cysteine, the pre-fluorescent dye rapidly transformed into a new structure and induced a fluorescent response clearly observable with the naked eye.
E. Karakuş, M. Sayar, S. Dartar, B. U. Kaya and M. Emrullahoğlu, Chem. Commun., 2019, 55, 4937 DOI: 10.1039/C9CC01774G
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