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Visualization of hERG channels in living cells via fluorescent probe regulated by the synergy between solvatochromism and molecular rotation based on a simple targeting group 4-benzylaniline

Abstract

A highly sensitive fluorescent probe CBH based on solvatochromism and molecular rotation was designed and developed for imaging of hERG channels by employing a novel targeting group 4-benzylaniline. More importantly, CBH has the potential for quantitative analysis of the hERG channels expressed in tumor cells.

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Publication details

The article was received on 02 Mar 2019, accepted on 09 Apr 2019 and first published on 11 Apr 2019


Article type: Communication
DOI: 10.1039/C9CC01735F
Citation: Chem. Commun., 2019, Accepted Manuscript

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    Visualization of hERG channels in living cells via fluorescent probe regulated by the synergy between solvatochromism and molecular rotation based on a simple targeting group 4-benzylaniline

    Z. Qiao, Q. Zhou, H. Zhang, N. Wei, Y. Zhang and K. Wang, Chem. Commun., 2019, Accepted Manuscript , DOI: 10.1039/C9CC01735F

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