Jump to main content
Jump to site search


The aryne Sommelet–Hauser rearrangement

Author affiliations

Abstract

An aryne induced transition-metal-free and mild Sommelet–Hauser rearrangement of tertiary benzylamines for the synthesis of α-aryl amino acid derivatives in moderate to good yields is presented. Unlike the conventional Sommelet–Hauser rearrangement of ammonium salts, the methodology developed herein requires neither harsh conditions nor strong bases. Moreover, a temperature dependent switchable selectivity for the Sommelet–Hauser and Stevens [1,2] rearrangements has been observed.

Graphical abstract: The aryne Sommelet–Hauser rearrangement

Back to tab navigation

Supplementary files

Publication details

The article was received on 23 Jan 2019, accepted on 11 Feb 2019 and first published on 12 Feb 2019


Article type: Communication
DOI: 10.1039/C9CC00629J
Citation: Chem. Commun., 2019, Advance Article

  •   Request permissions

    The aryne Sommelet–Hauser rearrangement

    T. Roy, R. N. Gaykar, S. Bhattacharjee and A. T. Biju, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C9CC00629J

Search articles by author

Spotlight

Advertisements