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Issue 28, 2019
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A thermoresponsive nanocarrier for mitochondria-targeted drug delivery

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Abstract

Mitochondria emerge as an important target for cancer therapy. Herein, by taking advantage of the recently reported high temperature of mitochondria, a well-tuned thermoresponsive nanocarrier was developed for specifically delivering the anticancer drug, paclitaxel (PTX), to mitochondria in cancer cells. The temperature-dependent delivery of drugs to mitochondria represents a novel anticancer strategy.

Graphical abstract: A thermoresponsive nanocarrier for mitochondria-targeted drug delivery

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Article information


Submitted
23 Jan 2019
Accepted
06 Mar 2019
First published
06 Mar 2019

Chem. Commun., 2019,55, 4051-4054
Article type
Communication

A thermoresponsive nanocarrier for mitochondria-targeted drug delivery

D. Wang, H. Huang, M. Zhou, H. Lu, J. Chen, Y. Chang, J. Gao, Z. Chai and Y. Hu, Chem. Commun., 2019, 55, 4051
DOI: 10.1039/C9CC00603F

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