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Issue 33, 2019
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A mitochondria targeting artesunate prodrug-loaded nanoparticle exerting anticancer activity via iron-mediated generation of the reactive oxygen species

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Abstract

An artesunate anticancer prodrug with a long aliphatic chain N,N′-bis(dodecyl)-L-glutamic diamide was developed into nanoparticle via iron-mediated ROS generation.

Graphical abstract: A mitochondria targeting artesunate prodrug-loaded nanoparticle exerting anticancer activity via iron-mediated generation of the reactive oxygen species

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Publication details

The article was received on 21 Jan 2019, accepted on 20 Mar 2019 and first published on 20 Mar 2019


Article type: Communication
DOI: 10.1039/C9CC00531E
Chem. Commun., 2019,55, 4781-4784

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    A mitochondria targeting artesunate prodrug-loaded nanoparticle exerting anticancer activity via iron-mediated generation of the reactive oxygen species

    Z. Chen, X. Kang, Y. Wu, H. Xiao, X. Cai, S. Sheng, X. Wang and S. Chen, Chem. Commun., 2019, 55, 4781
    DOI: 10.1039/C9CC00531E

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