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Issue 22, 2019
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Highly selective imaging of lysosomal azoreductase under hypoxia using pH-regulated and target-activated fluorescent nanoprobes

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Abstract

In this work, we propose a pH-regulated and target-activated fluorescent nanoprobe for highly selective monitoring of lysosomal azoreductase under hypoxia in living cells. We expect it will offer a potentially rich opportunity to understand the physiological processes of lysosomes under hypoxic conditions.

Graphical abstract: Highly selective imaging of lysosomal azoreductase under hypoxia using pH-regulated and target-activated fluorescent nanoprobes

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Publication details

The article was received on 21 Jan 2019, accepted on 13 Feb 2019 and first published on 15 Feb 2019


Article type: Communication
DOI: 10.1039/C9CC00462A
Chem. Commun., 2019,55, 3235-3238

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    Highly selective imaging of lysosomal azoreductase under hypoxia using pH-regulated and target-activated fluorescent nanoprobes

    C. Zhu, Z. Zou, C. Huang, J. Zheng, N. Liu, J. Li and R. Yang, Chem. Commun., 2019, 55, 3235
    DOI: 10.1039/C9CC00462A

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