Issue 17, 2019
From the journal:

Chemical Communications

A ratiometric fluorescent probe for detecting hypochlorite in the endoplasmic reticulum†

Ji-Ting Hou,‡ab   Hyeong Seok Kim,‡c   Chong Duan,‡d   Myung Sun Ji,c   Shan Wang,*ab   Lintao Zeng, ORCID logo *d   Wen Xiu Ren*ef  and  Jong Seung Kim ORCID logo *c  

* Corresponding authors

a Hubei Collaboration Innovation Center for Biomass Conversion and Utilization, School of Chemistry and Materials Science, Hubei Engineering University, Xiaogan 432000, P. R. China
E-mail: smallcoral@live.cn

b College of Chemistry and Chemical Engineering, Xinyang Normal University, Xinyang 464000, P. R. China

c Department of Chemistry, Korea University, Seoul 02841, Korea
E-mail: jongskim@korea.ac.kr

d School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin, P. R. China
E-mail: zlt1981@126.com

e Department of Radiology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, P. R. China
E-mail: xrenwenxiux@hotmail.com

f Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, P. R. China

Abstract

A colorimetric and fluorescent probe ER-ClO was presented in this work to detect cellular hypochlorite with high selectivity and sensitivity. With an organelle targeting unit, ER-ClO was successfully applied in the bio-imaging of exogenous and endogenous hypochlorite in the endoplasmic reticulum in a ratiometric manner.

Graphical abstract: A ratiometric fluorescent probe for detecting hypochlorite in the endoplasmic reticulum

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Article information

DOI
https://doi.org/10.1039/C9CC00066F
Article type
Communication
Submitted
04 Jan 2019
Accepted
01 Feb 2019
First published
01 Feb 2019

Chem. Commun., 2019,55, 2533-2536

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A ratiometric fluorescent probe for detecting hypochlorite in the endoplasmic reticulum

J. Hou, H. S. Kim, C. Duan, M. S. Ji, S. Wang, L. Zeng, W. X. Ren and J. S. Kim, Chem. Commun., 2019, 55, 2533 DOI: 10.1039/C9CC00066F

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