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Issue 22, 2019
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One-step co-assembly method to fabricate photosensitive peptide nanoparticles for two-photon photodynamic therapy

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Abstract

Peptide-based nanoparticles were employed to load and disperse hydrophobic porphyrins in a one-step co-assembly method in aqueous media. The isolated porphyrins doped within nanoparticles showed enhanced two-photon absorption ability and could effectively generate 1O2 to induce the apoptosis of cancer cells, which holds great prospects in two-photon PDT.

Graphical abstract: One-step co-assembly method to fabricate photosensitive peptide nanoparticles for two-photon photodynamic therapy

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Publication details

The article was received on 02 Jan 2019, accepted on 29 Jan 2019 and first published on 31 Jan 2019


Article type: Communication
DOI: 10.1039/C9CC00025A
Citation: Chem. Commun., 2019,55, 3191-3194

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    One-step co-assembly method to fabricate photosensitive peptide nanoparticles for two-photon photodynamic therapy

    J. Li, A. Wang, P. Ren, X. Yan and S. Bai, Chem. Commun., 2019, 55, 3191
    DOI: 10.1039/C9CC00025A

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